Without photoexposure

Until now the only strategy that has proven to prolong life is caloric restriction. This leads to lower incidence of diabetes, cataracts, cardiovascular and renal disease.

It is believed that 2% (Night Comfort Review) of the genes change their expression with aging, 921 of them do so with caloric restriction and 947 genes with the use of resveratrol.

In rats with caloric restriction compared to free-fed controls, both without photoexposure Night Comfort Review, an increase in vasculature, connective tissue and fibroblast activity was found.